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Chiurchiù, V. (2016). Endocannabinoids and Immunity. Cannabis and cannabinoid research, 1(1), 59–66. Added by: Dr. Enrique Feoli (15/06/2020, 14:45) |
| Resource type: Journal Article DOI: 10.1089/can.2016.0002 ID no. (ISBN etc.): 2378-8763 BibTeX citation key: 2016 View all bibliographic details |
Categories: Mendeley, Mendeley Subcategories: Analgesia Creators: Chiurchiù Collection: Cannabis and cannabinoid research |
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| Abstract |
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Over the last 10 years, a great boost of knowledge accumulated on the immunomodulatory and anti-inflammatory properties of endocannabinoids (eCBs). In this scenario, these bioactive lipids, which are produced by most immune cells along with a set of receptors and enzymes that regulate their synthesis and degradation, act as secondary modulators and increase or decrease a plethora of immune functions. In this review, the manifold immunomodulatory effects of the main eCBs in different compartments of innate and adaptive immunity will be discussed, suggesting that they could be considered as master regulators of innate-adaptive immune axis and as potent immunoresolvents.
Added by: Dr. Enrique Feoli |