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Divangahi, M., Khan, N., & Kaufmann, E. (2018). Beyond Killing Mycobacterium tuberculosis: Disease Tolerance. Frontiers in immunology, 9. 
Added by: Dr. Enrique Feoli (15/07/2020, 14:41)   Last edited by: Dr. Enrique Feoli (15/07/2020, 14:46)
Resource type: Journal Article
DOI: 10.3389/fimmu.2018.02976
ID no. (ISBN etc.): 1664-3224
BibTeX citation key: Divangahi2018
View all bibliographic details
 Categories: Zotero
Subcategories: Tolerancia Mycobacterium
Creators: Divangahi, Kaufmann, Khan
Collection: Frontiers in immunology		 Views: 2/222
Abstract
Host defense strategies against infectious diseases are comprised of both host resistance and disease tolerance. Resistance is the ability of the host to prevent invasion or to eliminate the pathogen, while disease tolerance is defined by limiting the collateral tissue damage caused by the pathogen and/or the immune response without exerting direct effects on pathogen growth. Our incomplete understanding of host immunity against tuberculosis (TB) is predominately rooted in our bias toward investigating host resistance. Thus, we must refocus our efforts to understand the entire spectrum of immunity against M. tuberculosis to control TB.
  
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