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Soares, M. P., Teixeira, L., & Moita, L. F. (2017). Disease tolerance and immunity in host protection against infection. Nature Reviews Immunology, 17(2), 83–96. 
Added by: Dr. Enrique Feoli (03/09/2025, 22:04)   Last edited by: Dr. Enrique Feoli (03/09/2025, 22:05)
Resource type: Journal Article
DOI: 10.1038/nri.2016.136
ID no. (ISBN etc.): 1474-1741
BibTeX citation key: Soares2017
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 Categories: BioAcyl Corp
Subcategories: Disease Tolerance
Keywords: Antimicrobial responses, infection, inflammation, Lymphoid tissues
Creators: Moita, Soares, Teixeira
Collection: Nature Reviews Immunology		 Views: 3/24
Abstract
Disease tolerance is an evolutionarily conserved defence strategy against infection that does not exert a direct negative effect on the host pathogen load.Disease tolerance relies on tissue damage control mechanisms.Tissue damage control mechanisms rely on stress and damage responses.Innate and adaptive components of the immune system regulate tissue damage control mechanisms and contribute to the establishment of disease tolerance to infection.Host–commensal microorganism interactions regulate disease tolerance against pathogens.Pharmacological targeting of tissue damage control mechanisms induces disease tolerance to infection.
  
Notes
Publisher: Nature Publishing Group
  
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