Innate immunity and epigenetic plasticity in cellular reprogramming

Cooke, John P.; Sayed, Nazish; Lee, Jieun

doi:10.1016/j.gde.2014.11.002

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BioAcyl Corp

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Cooke, J. P., Sayed, N., & Lee, J. (2014). Innate immunity and epigenetic plasticity in cellular reprogramming. Current opinion in genetics & development, 89–91.
Added by: Dr. Enrique Feoli (21/05/2023, 15:06) Last edited by: Dr. Enrique Feoli (21/05/2023, 15:07)

Resource type: Journal Article
DOI: 10.1016/j.gde.2014.11.002
ID no. (ISBN etc.): 0959-437X
BibTeX citation key: Cooke2014
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Categories: BioAcyl Corp
Subcategories: Stemness
Creators: Cooke, Lee, Sayed
Collection: Current opinion in genetics & development

Views: 2/703

Abstract

Somatic cells can be reprogrammed to express the features of pluripotent cells, in that they can be differentiated into all three germ layers, and that they have the ability to replicate indefinitely. Recent studies suggest that the efficient induction of pluripotency requires the activation of innate immunity.