BioAcyl Corp
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Liu, Y., Lou, W. P.-K., & Fei, J.-F. (2021). The engine initiating tissue regeneration: Does a common mechanism exist during evolution? Cell Regeneration, 10(1), 12. Added by: Dr. Enrique Feoli (30/04/2023, 16:54) Last edited by: Dr. Enrique Feoli (30/04/2023, 17:23) |
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| Resource type: Journal Article DOI: 10.1186/s13619-020-00073-1 ID no. (ISBN etc.): 2045-9769 BibTeX citation key: Liu2021 View all bibliographic details  |
Categories: BioAcyl Corp Subcategories: Post-injury Regeneration Creators: Fei, Liu, Lou Collection: Cell Regeneration |
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| Abstract |
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A successful tissue regeneration is a very complex process that requires a precise coordination of many molecular, cellular and physiological events. One of the critical steps is to convert the injury signals into regeneration signals to initiate tissue regeneration. Although many efforts have been made to investigate the mechanisms triggering tissue regeneration, the fundamental questions remain unresolved. One of the major obstacles is that the injury and the initiation of regeneration are two highly coupled processes and hard to separate from one another. In this article, we review the major events occurring at the early injury/regeneration stage in a range of species, and discuss the possible common mechanisms during initiation of tissue regeneration.
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| Notes |
The interaction of tissue injury, the injury-induced early wound responses and progenitor activation, occurring immediately after injury or at the early stage of regeneration. Black solid arrows represent the confirmed interactions based on the studies from regenerative organisms; Red dashed arrows indicate potential interactions |