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Lundberg, O. J., Weitzberg, E., Reviews ldots, J. C.-. N., & 2004. (2003). Nitrate, bacteria and human health. Nature Reviews Microbiology. Added by: Dr. Enrique Feoli (22/07/2020, 20:07) Last edited by: Dr. Enrique Feoli (22/07/2020, 20:10) |
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| Resource type: Journal Article BibTeX citation key: Lundberg2003 View all bibliographic details  |
Categories: BioAcyl Corp Subcategories: Inmunidad de mucosas Creators: 2004, Lundberg, Reviews ldots, Weitzberg Collection: Nature Reviews Microbiology |
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| Abstract |
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Nitrate is generally considered a water pollutant and an undesirable fertilizer residue in the food chain. Research in the 1970s indicated that, by reducing nitrate to nitrite, commensal bacteria might be involved in the pathogenesis of gastric cancers and other malignancies, as nitrite can enhance the generation of carcinogenic N-nitrosamines. More recent studies indicate that the bacterial metabolism of nitrate to nitrite and the subsequent formation of biologically active nitrogen oxides could be beneficial. Here, we will consider the evidence that nitrate-reducing commensals have a true symbiotic role in mammals and facilitate a previously unrecognized but potentially important aspect of the nitrogen cycle.
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