BioAcyl Corp
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Xue, L., An, R., & Zhao, J. (2025). Self-healing hydrogels: Mechanisms and biomedical applications. MedComm, 6(5), e70181. Added by: Dr. Enrique Feoli (25/07/2025, 00:16) Last edited by: Dr. Enrique Feoli (25/07/2025, 00:25) |
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| Resource type: Journal Article DOI: 10.1002/mco2.70181 BibTeX citation key: Xue2025 View all bibliographic details  |
Categories: BioAcyl Corp Subcategories: Self healing hydrogels Keywords: biomedical applications, hydrogels, self-healing mechanisms Creators: An, Xue, Zhao Collection: MedComm |
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| Abstract |
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ABSTRACT Hydrogels have emerged as dependable candidates for tissue repair because of their exceptional biocompatibility and tunable mechanical properties. However, conventional hydrogels are vulnerable to damage owing to mechanical stress and environmental factors that compromise their structural integrity and reduce their lifespan. In contrast, self-healing hydrogels with their inherent ability to restore structure and function autonomously offer prolonged efficacy and enhanced appeal. These hydrogels can be engineered into innovative forms including stimulus-responsive, self-degradable, injectable, and drug-loaded variants, thereby enhancing their applicability in wound healing, drug delivery, and tissue engineering. This review summarizes the categories and mechanisms of self-healing hydrogels, along with their biomedical applications, including tissue repair, drug delivery, and biosensing. Tissue repair includes wound healing, bone-related repair, nerve repair, and cardiac repair. Additionally, we explored the challenges that self-healing hydrogels continue to face in tissue repair and presented a forward-looking perspective on their development. Consequently, it is anticipated that self-healing hydrogels will be progressively designed and developed for applications that extend beyond tissue repair to a broader range of biomedical applications.
Self-healing hydrogels: their mechanism and biological applications. (E-A complex-based polyacrylamide [EACPA] hydrogel; kappa-carrageenan-dopamine functionalized graphene oxide [KaMA-GOPD] hydrogel; electroconductive [ECH] hydrogel; conductive and adhesive [CAH] hydrogel). Added by: Dr. Enrique Feoli Last edited by: Dr. Enrique Feoli |
